Flu Jab May Help Lower Alzheimer’s Risk in Over-65s, Study Suggests

Flu Jab May Help Lower Alzheimer’s Risk in Over-65s, Study Suggests

A new study published in Neurology has found that older adults who receive a high-dose flu vaccine may be less likely to develop Alzheimer’s disease.

The research adds to growing evidence that vaccines could help protect not just physical health, but also brain health as people age.

What the study found

Researchers looked at health records from over 160,000 people aged 65 and above. They compared those who had a high-dose flu jab with those who had the standard version.

They found that people who received the stronger vaccine were much less likely to develop Alzheimer’s disease over the following years.

The high-dose vaccine is designed especially for older adults, as it helps create a stronger immune response.

Why might this happen?

The study doesn’t prove exactly why this link exists, but researchers have some ideas.

They believe the vaccine may:

  • Help the body fight off infections more effectively
  • Reduce inflammation in the body and brain
  • Protect the brain from damage linked to illness

Since inflammation is linked to dementia, reducing it could help lower the risk.

Who benefits most?

Both men and women appeared to benefit from the high-dose flu jab. However, the study suggested the effect may last longer in women.

There are also signs that having the vaccine every year could give even more protection.

What this means for care

For people working in health and social care, the findings highlight the importance of encouraging flu vaccinations in older adults.

It shows that the flu jab could:

  • Help prevent illness
  • Support long-term brain health
  • Be part of a wider approach to healthy ageing

Key message

The flu vaccine is already important for protecting against illness, but this study suggests it may also help reduce the risk of Alzheimer’s disease. While more research is needed, it’s another reason to support vaccination in later life.